Endocrine Abstracts

73-year-old gentleman presented to AEC with 3-week history of shortness of breath, cough with sputum production, generalised weakness and loss of appetite. He was found to have iron deficiency anaemia and hyponatraemia (120mmol/l). He had history of type2 diabetes, and hypertension. On workup for hyponatremia, both free T3 and free T4 are reduced with suppressed TSH 0.01 uIU/ml. TSH receptor antibody was negative. He was started on levothyroxine 50mg on suspicion of secondary ...

A 50 year old Asian lady developed neck pain and sore throat 10 days after first dose of AstraZeneca COVID-19 vaccination. Her dentist thought she had tonsillitis. She then presented to hospital a few days later with dyspnoea, palpitations, tremor and neck pain. She was apyrexial but clinically thyrotoxic with sinus tachycardia. Thyroid gland had normal size with tenderness without bruit or lymphadenopathy. Her Free T4 was >100 pmol/l (11.2 - 20.2), TSH < 0.01mIU/l, ES...

Here we present two interesting cases of pheochromocytoma with unusual presentation. Case1: A 61-year-old gentleman presented with syncope after noticing small amount of haematuria. His initial working diagnosis was vasovagal syncope but on further exploration, he reported previous history of palpitations and atypical chest pain. He was non-smoker with longstanding hypertension. His CT(urogram) showed incidental left adrenal nodule after...

The COVID-19 vaccine plays an important role in managing the pandemic. Unfortunately, there are endocrine side effects also noted. The 36-year-old lady felt unwell 2 weeks post-AstraZeneca COVID-19 vaccine. She got admitted to the hospital after 6weeks with persistent vomiting and significant hyponatremia. She has a past history of well-controlled asthma and hypothyroidism. Random cortisol on admission was 31 nmol/l, and a short synacthen test(SST) confirmed adrenal insufficie...

Hypocalcaemia can present with paraesthesia, twitching, mood and memory changes and should be considered a medical emergency given potential to cause seizures, tetany, arrhythmia and cardiac arrest. It may be caused by hormonal dysregulation including hypoparathyroidism or pseudohypoparathyroidism or other factors such as vitamin D deficiency, chronic kidney disease or hypomagnesaemia. In this case series, we highlight the use of various protein pump inhibitors (PPIs) in drivi...